Cotinine Half Life at Life

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Cotinine Half Life. Cotinine can be detected in various test samples, including urine, blood and saliva. And for some heavy smokers, it can take about 3 weeks.

Assessing secondhand smoke using biological markers
Assessing secondhand smoke using biological markers from tobaccocontrol.bmj.com

Cotinine merupakan indikator penting yang dipaparkan oleh asap rokok, bahkan pada perokok pasif pun, karena jumlah cotinine dalam darah. Peak brain concentrations of nicotine metabolites were 300, 70, and 7 nm for cotinine, nornicotine, and norcotinine, respectively. It can take more than 2 weeks for cotinine levels to drop to those typical of a nonsmoker.

Assessing secondhand smoke using biological markers

Most tobacco users excrete cotinine in the range of 1,000 to 8,000 ng/ml. Cotinine accumulates in urine in proportion to dose and hepatic metabolism (which is genetically determined); It can be detected in plasma, urine, and saliva. Cotinine is a chemical your body makes after you are exposed to nicotine.