Diltiazem Half Life at Life

Diltiazem Half Life. Binding studies show cardizem is 70% to 80% bound to plasma proteins. So it's safe to say that it has been completely eliminated from your blood by now.

Therapeutic blood levels of diltiazem appear to be in the range of 40 to 200 ng/ml. In vitro binding studies show diltiazem is 70% to 80% bound to plasma proteins. Less than 5% of diltiazem is excreted unchanged in the urine.

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In vitro human serum binding studies revealed that 70 to 80% of diltiazem is bound to plasma proteins. So it's safe to say that it has been completely eliminated from your blood by now. Total radioactivity measurement following short iv administration in healthy volunteers suggests the presence of other unidentified metabolites, which attain higher concentrations than those of diltiazem and are more slowly eliminated; Desacetyl diltiazem is also present in the plasma at levels of 10% to 20% of the parent drug and is 25% to 50% as potent as a coronary vasodilator as diltiazem.